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Thursday, November 5, 2015

The incidence and risk factors of deep vein thrombosis after kidney transplantation in Korea: single center experience

Clinical Transplantation The incidence and risk factors of deep vein thrombosis after kidney transplantation in Korea: single center experience

Abstract

Background

The incidence of deep vein thrombosis (DVT) after kidney transplantation (KT) and the risk factors are still unknown in Korean patients. Determining the need for appropriate DVT prophylaxis is difficult when considering the low incidence of DVT in the Asian population. The aim of the present study was to investigate the incidence of DVT occurring 3 months after KT, the DVT occurrence pattern, and risk factors in Korean patients.

Methods

Data from a total of 393 patients who underwent KT from November 2009 to December 2012 were analyzed. Color duplex ultrasonography was used for the diagnosis or screening of DVT in all patients preoperatively and on postoperative day 7, 14, 28 and 90.

Results

The cumulative 3 months incidence of DVT after KT was 4.6%, and there was one symptomatic DVT. Patients with DVT were older than those without DVT at the time of transplantation (52.8 vs. 44.6, P < 0.001). According to univariate and multivariate analysis, older age was identified as a risk factor of DVT at the time of transplantation, whereas history of DVT did not reach statistical significance. There were no deaths related to DVT or pulmonary embolism.

Conclusions

Pharmacological prophylaxis after KT is not necessary because of the low incidence of DVT in Korean patients, and instead, we suggest that long-term mechanical prophylaxis of at least 3 months can be a suitable option. Patients older than 50 years of age have a higher risk of developing DVT, and careful observation is needed in these patients.

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http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fctr.12648

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Alberto Reino Buelvas 
Médico Internista Nefrólogo


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