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Showing posts with label Aspergillus. Show all posts
Showing posts with label Aspergillus. Show all posts

Friday, September 30, 2011

False-positive Aspergillus galactomannan assay in solid organ transplant recipients with histoplasmosis

False-positive Aspergillus galactomannan assay in solid organ transplant recipients with histoplasmosis:

Abstract:

Post-transplantation histoplasmosis may be acquired via inhalation, may result from endogenous reactivation, or may be derived from the allograft. The Histoplasma and Aspergillus enzyme-linked immunoassays are increasingly being relied upon for rapid diagnosis of fungal infections, especially in immunocompromised patients. We describe 4 cases of solid organ transplant recipients who had histoplasmosis and a falsely positive Aspergillus galactomannan (GM) obtained from the serum or bronchoalveolar lavage (BAL) fluid.